Quantum protons in hydrogen bonds

NMR localization of protons in critical enzyme hydrogen bonds.

Shasad Sharif,‡ Emily Fogle,† Michael D. Toney,† Gleb S. Denisov,§ Ilya G. Shenderovich,‡ Gerd Buntkowsky,¶ Peter M. Tolstoy,‡ Monique Chan Huot,‡ and Hans-Heinrich Limbach*,‡ Institut für Chemie und Biochemie, Takustrasse 3, Freie UniVersität Berlin, D-14195 Berlin, Germany, Institute of Physics, St. Petersburg State UniVersity, 198504 St. Petersburg, Russian Federation, Department of Chemistr...

Concerted motion of protons in hydrogen bonds of DNA-type molecules

Concerted motion of protons in hydrogen bonds of DNA-type molecules. Abstract We study the dynamical behaviour of the proton transfer in the hydrogen bonds in the base-pairs of the double helices of the DNA type. Under the assumption that the elastic and the tunnelling degrees of freedom may be coupled, we derive a non-linear and non-local Schrodinger equation (SNLNL) that describes the concert...

Hydrogen Bonds

Field-dependent Mechanism of Anomalous Proton Conductivity and the Polarizability of Hydrogen Bonds with Tunneling Protons

The displacement of the excess charge of the proton in acid solutions is caused by a structure migration of groupings H 5 0 2 + or H 9 0 4 + . The processes which take place during structure migration are discussed on the basis of results gained in IR-investigations. In an electrical field the structure migration is given a preferred direction. The hydrogen bond with the tunneling proton in H 5...

Short hydrogen bonds in proteins.

Short hydrogen bonds are present in many chemical and biological systems. It is well known that these short hydrogen bonds are found in the active site of enzymes and aid enzyme catalysis. This study aims to systematically characterize all short hydrogen bonds from a nonredundant dataset of protein structures. The study has revealed that short hydrogen bonds are commonly found in proteins and a...